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Maria Fatima Grossi-de-Sa

Filiation:                                       Embrapa Genetic Resources and Biotechnology

                                                     PqEB, W5 Norte (end), Biotechnology Building, P.O. Box 02372

                                                     Brasília-DF, Brazil - Postal Code 70770-917

E-mail:                                          fatima.grossi@embrapa.br

Telephone:                                   +55 (61) 99965-6736

Google Scholar:                            https://scholar.google.com.br/citations?user=Dby5KykAAAAJ&hl=en

Research Gate:                             https://www.researchgate.net/profile/Maria-Grossi-De-Sa

Lattes website (in Portuguese):  http://lattes.cnpq.br/3058512809761818

Scopus Author ID:                       7003331016

Web of Science Researcher ID:   N-7856-2017

ORCID ID:                                    https://orcid.org/0000-0001-8184-9599

PROFILE

 

          Maria Fatima Grossi-de-Sa is a Researcher Group Leader at EMBRAPA Genetic Resources and Biotechnology and Professor at the Catholic University of Brasília, Brasília-DF, Brazil. She is also the Coordinator of the National Institute of Science and Technology – INCT PlantStress Biotech at EMBRAPA and Director President of the Brazilian Society of Biotechnology. She is a full member of the Brazilian Academy of Sciences and the World Academy of Science (TWAS). In 2018, she received the Commander medal of the National Order of Scientific Merit. She heads the Plant Pest Molecular Interaction Laboratory and works in a wide range of research interests with an emphasis on plant biotechnology. Her main research interest are plant pest’s molecular interactions focused on phytonematodes and insect-pests, the development of GM crop plants for tolerance/resistance to abiotic stress and biotic stresses, the understanding of the molecular RNAi mechanism on insect pests, and the development of biopharmaceuticals. She is classified as scientific researcher 1A at Brazilian National Research Council (CNPq), has coordinated several research projects at EMBRAPA, FAP-DF, CAPES, and CNPq, and currently, her research group is also funded by industry and the productive sector of agribusiness.

EDUCATION

 

  • B.Sc. In Biological Sciences, University of Brasilia, Brazil, 1979.

  • M.Sc.  In Molecular Biology, University of Brasilia, Brazil, 1982. 

  • Ph.D. University PARIS VII, Paris, France, 1987.

CURRENT POSITION

 

  • Researcher Leader on Plant Biotechnology at EMBRAPA Genetic Resources and Biotechnology - Brasilia- DF, Brazil (since 1989).

  • Senior Associate Professor at Catholic University of Brasilia (UCB), Brasilia-DF, Brazil (since 2004).

  • President of Brazilian Society of Biotechnology (since 2016).

  • Director of the National Institute Science & Technology on Plant Stress Biotechnology (INCT PlantStress Biotech; since 2016).

HONOURS/AWARDS

 

  • Award of Excellence in recognition of Outstanding Research Performance by Embrapa (2009).

  • Award Brazil SCOPUS Awards 2010 - Elsevier/CAPES (2010).

  • Full elected member of Brazilian Academy of Sciences (Elected May 2011).

  • Full elected member of the World Academy of Sciences (Elected Nov 2014).

  • National Order of Scientific Merit - Commander Class, Ministry of Science and Technology - Presidency of the Republic (2018).

RESEARCH INTERESTS

 

          The main research interests focusing on novel and innovative approaches to crop protection, which cover, plant-nematode and insect interactions, transgenic crops, biotic and abiotic stresses, plant genome editing, gene silencing, insect nanobiotechnology, biopesticides based on RNA interference approaches, and recombinant proteins.

RELEVANT PAPERS (LAST 7 YEARS)

 

2021

MENDES, R.A.G.; Basso, M.F.; Paes-Melo, B.; Ribeiro, T.P.; Lima, R.N.; Araujo, J.F.; Grossi-de-Sa, M.; Mattos, V.S.; Togawa, R.C.; Albuquerque, E.V.S.; Lisei-de-Sa, M.E.; Silva, M.C.M.; Macedo, L.L.P.; Fragoso, R.R.; Fernandez, D.; Vignols, F.; Grossi-de-Sa, M.F. (2021). The Mi-EFF1/Minc17998 effector interacts with the soybean GmHub6 protein to promote host plant parasitism by Meloidogyne incognita. Physiological and Molecular Plant Pathology, v. 114, p. 101630.

 

2020

ARRAES, F.B.M.; Martins-de-Sa, D.; Noriega-Vasquez, D.D.; Paes-Melo, B.; Faheem, M.; Macedo, L.L.P.; Morgante, C.V.; Barbosa, J.A.R.; Togawa, R.C.; Vaz-Moreira, V.J.; Danchin, E.G.J.; Grossi-de-Sa, M.F. (2020). Dissecting protein domain variability in the core RNA interference machinery of five insect orders. RNA Biology, v. 31, p. 1-29.

 

BASSO, M.F.; Arraes, F.B.M.; Grossi-de-Sa, M.; Vaz-Moreira, V.J.; Alves-Ferreira, M.; Grossi-de-Sa, M.F. (2020). Insights into genetic and molecular elements for transgenic crop development. Frontiers in Plant Science, v. 11, p. 509.

 

BASSO, M.F.; Lourenço-Tessutti, I.T.; Busanello, C.; Pinto, C.E.M.; Oliveira-Freitas, E.; Ribeiro, T.P.; Almeida-Engler, J.; Oliveira, A.C.; Morgante, C.V.; Alves-Ferreira, M.; Grossi-de-Sa, M.F. (2020). Insights obtained using different modules of the cotton uceA1.7 promoter. Planta, v. 251, p. 56.

 

BASSO, M.F.; Lourenço-Tessutti, I.T.; Mendes, R.A.G.; Pinto, C.E.M.; Bournaud, C.; Gillet, F.X.; Togawa, R.C.; Macedo, L.L.P.; Almeida-Engler, J.; Grossi-de-Sa, M.F. (2020). MiDaf16-like and MiSkn1-like gene families are reliable targets to develop biotechnological tools for the control and management of Meloidogyne incognita. Scientific Reports, v. 10, p. 6991.

 

BEVITORI, R.; Sircar, S.; Mello, R.N.; Togawa, R.C.; Cortes, M.V.C.B.; Oliveira, T.S.; Grossi-de-Sa, M.F.; Parekh, N. (2020). Identification of co-expression gene networks controlling rice blast disease during an incompatible reaction. Genetics Molecular Research, v. 19, p. gmr18579.

 

CABRAL, D.N.; Banora, M.Y.; Antonino, J.D.; Rodiuc, N.; Vieira, P.; Coelho, R.R.; Chevalier, C.; Eekhout, T.; Engler G.; De-Veylder, L.; Grossi-de-Sa, M.F.; Almeida-Engler, J. (2020). The plant WEE1 kinase is involved in checkpoint control activation in nematode-induced galls. New Phytologist, v. 225(1), p. 430-447.

 

CAMPOS, M.L.; Prado, G.S.; Santos, V.O.; Nascimento, L.C.; Dohms, S.M.; Cunha, N.B.; Ramada, M.H.S.; Grossi-de-Sa, M.F.; Dias, S.C. (2020). Mosses: versatile plants for biotechnological applications. Biotechnology Advances, v. 6, p. 107533.

 

FIRMINO, A.A.P.; Pinheiro, D.H.; Pinto, C.E.M.; Antonino, J.D.; Macedo, L.L.P.; Martins-de-Sa, D.; Arraes, F.B.M.; Coelho, R.R.; Fonseca, F.C.A.; Silva, M.C.M.; Almeida-Engler, J.; Silva, M.S.; Lourenço-Tessutti, I.T.; Terra, W.R.; Grossi-de-Sa, M.F. (2020). RNAi-mediated suppression of Laccase2 impairs cuticle tanning and molting in the cotton boll weevil (Anthonomus grandis). Frontiers in Physiology, v. 11, p. 591569.


GRYNBERG, P.; Togawa, R.C.; Freitas, L.D.; Antonino, J.D.; Rancurel, C.; Costa, M.M.C.; Grossi-de-Sa, M.F.; Miller, R.N.G.; Brasileiro, A.C.M.; Guimaraes, P.M.; Danchin, E.G.J. (2020). Comparative genomics reveals novel target genes towards specific control of plant-parasitic nematodes. Genes, v. 11, p. 1347. 

IBARRA, L.N.; Alves, A.E.O.A.; Antonino, J.D.; Prado, G.S.; Pinto, C.E.M.; Soccol, C.R.; Vasconcelos, E.A.R.; Grossi-de-Sa, M.F. (2020). Enzymatic activity of a recombinant β-1,4-endoglucanase from the cotton boll weevil (Anthonomus grandis) aiming second generation ethanol production. Scientific Reports, v. 10(1), p. 5367.

 

MOTA, A.P.Z.; Fernandez, D.; Arraes, F.B.M.; Petitot, A.S.; Paes-Melo, B.; Lisei-de-Sa, M.E.; Guimaraes, P.M.; Brasileiro, A.C.M.; Albuquerque, E.V.S.; Danchin, E.G.J.; Grossi-de-Sa, M.F. (2020). Evolutionarily conserved plant genes responsive to root-knot nematodes identified by comparative genomics. Molecular Genetics and Genomics, v. 295, p. 1063-1078.

 

MOURA, S.M.; Rossi, M.L.; Artico, S.; Grossi-de-Sa, M.F.; Martinelli, A.P.; Alves-Ferreira, M. (2020). Characterization of floral morphoanatomy and identification of marker genes preferentially expressed during specific stages of cotton flower development. Planta, v. 252(4), p. 71.

 

NORIEGA-VASQUEZ, D.D.; Arraes, F.B.M.; Antonino, J.D.; Macedo, L.L.P.; Fonseca, F.C.A.; Togawa, R.C.; Grynberg, P.; Silva, M.C.M.; Negrisoli, A.S.; Grossi-de-Sa, M.F. (2020). Transcriptome analysis and knockdown of the juvenile hormone esterase gene reveal abnormal feeding behavior in the sugarcane giant borer. Frontiers in Physiology, v. 11, p. 588450.

 

NORIEGA-VASQUEZ, D.D.; Arraes, F.B.M.; Antonino, J.D.; Macedo, L.L.P.; Fonseca, F.C.A.; Togawa, R.C.; Grynberg, P.; Silva, M.C.M.; Negrisoli, A.S.; Morgante, C.V.; Grossi-de-Sa, M.F. (2020). Comparative gut transcriptome analysis of Diatraea saccharalis in response to the dietary source. PLoS One, v. 15(8), p. e0235575.

 

PAES-MELO, B.; Lourenço-Tessutti, I.T.; Morgante, C.V.; Santos, N.C.; Pinheiro, L.B.; Jesus-Lins, C.B.; Silva, M.C.M.; Macedo, L.L.P.; Fontes, E.P.B.; Grossi-de-Sa, M.F. (2020). Soybean embryonic axis transformation: combining biolistic and Agrobacterium-mediated protocols to overcome typical complications of in vitro plant regeneration. Frontiers in Plant Science, v. 11, p. 1228.

 

PAES-MELO, B.; Lourenço-Tessutti, I.T.; Paixao, J.F.R.; Noriega-Vasquez, D.D.; Silva, M.C.M.; Almeida-Engler, J.; Fontes, E.P.B.; Grossi-de-Sa, M.F. (2020). Transcriptional modulation of AREB-1 by CRISPRa improves plant physiological performance under severe water deficit. Scientific Reports, v. 10(1), p. 16231.


RIBEIRO, T.P.; Basso, M.F.; Carvalho, M.H.; Macedo, L.L.P.; Silva, D.M.L.S.; Lourenço-Tessutti, I.T.; Oliveira-Neto, O.B.; Romano, E.; Lucena, W.A.; Silva, M.C.M.; Tripode, B.M.D.; Abreu-Jardin, T.P.F.; Miranda, J.E.; Alves-Ferreira, M.; Morgante, C.V.; Grossi-de-Sa, M.F. (2020). Stability and tissue-specific Cry10Aa overexpression improves cotton resistance to the cotton boll weevil. Biotechnology Research & Innovation, v. 3, p. 15.

SANTOS, C.; Nogueira, F.C.S.; Domont, G.B.; Fontes, W.; Prado, G.S.; Habibi, P.; Santos, V.O.; Oliveira-Neto, O.B.; Grossi-de-Sa, M.F.; Jorrín-Novo, J.V.; Franco, O.L.; Mehta, A. (2020). Proteomic analysis and functional validation of a Brassica oleracea endochitinase involved in resistance to Xanthomonas campestres. Frontiers in Plant Science, v. 11, p. 201.

2019

BASSO, A.M.M.; Castro, R.J.A.; Castro, T.B.; Guimaraes, H.I.; Polez, V.L.P.; Carbonero, E.R.; Pomin, V.H.; Hoffmann, C.; Grossi-de-Sa, M.F.; Tavares, A.H.; Bocca, A.L. (2019). Immunomodulatory activity of β-glucan-containing exopolysaccharides from Auricularia auricular in phagocytes and mice infected with Cryptococcus neoformans. Medical Mycology, v. 58(2), p. 227-239.

 

BASSO, M.F.; Ferreira, P.C.G.; Kobayashi, A.K.; Harmon, F.G.; Nepomuceno, A.L.; Molinari, H.B.C.; Grossi-de-Sa, M.F. (2019). MicroRNAs and new biotechnological tools for its modulation and improving stress tolerance in plants. Plant Biotechnology Journal, v. 17(8), p. 1482-1500.

 

FIGUEIREDO, L.H.M.; Vasconcellos, A.G.; Prado, G.S.; Grossi-de-Sa, M.F. (2019). An overview of intellectual property within agricultural biotechnology in Brazil. Biotechnology Research & Innovation, v. 3(1), p. 69-79.

 

FREITAS, E.O.; Paes-Melo, B.; Lourenço-Tessutti, I.T.; Arraes, F.B.M.; Amorim, R.M.S.; Lisei-de-Sa, M.E.; Costa, J.A.; Leite, A.G.B.; Faheem, M.; Ferreira, M.A.; Morgante, C.V.; Fontes, E.P.B.; Grossi-de-Sa, M.F. (2019). Identification and characterization of the GmRD26 soybean promoter in response to abiotic stresses: potential tool for biotechnological application. BMC Biotechnology, v. 19(1), p. 79.

 

GROSSI-DE-SA, M.; Petitot, A.S.; Xavier, D.A.; Lisei-de-Sa, M.E.; Mezzalira, I.; Beneventi, M.A.; Martins, N.F.; Baimey, H.K.; Albuquerque, E.V.S.; Grossi-de-Sa, M.F.; Fernandez, D. (2019). Rice susceptibility to root-knot nematodes is enhanced by the Meloidogyne incognita MSP18 effector gene. Planta, v. 250, p. 1215-1227.

 

HABIBI, P. ; Henry, D.; Soccol, C.R.; Grossi-de-Sa, M.F. (2019). The potential of plant systems to break the HIV-TB link. Plant Biotechnology Journal, v. 17(10), p. 1868-1891.

 

MATTOS, V.S.; Mulet, K.; Cares, J.E.; Gomes, C.B.; Fernandez, D.; Grossi-de-Sa, M.F.; Carneiro, R.M.D.G.; Castagnone-Sereno, P. (2019). Development of diagnostic SCAR markers for Meloidogyne graminicolaM. oryzae, and M. salasi associated with irrigated rice fields in Americas. Plant Disease, v. 103, p. 83-88.

 

MOTA, A.P.Z.; Oliveira, T.N.; Vinson, C.C.; Williams, T.C.R.; Costa, M.M.C.; Araujo, A.C.G.; Danchin, E.G.J.; Grossi-de-Sa, M.F.; Guimaraes, P.M.; Brasileiro, A.C.M. (2019). Effects of wild Arachis dehydrin under abiotic and biotic stresses. Frontiers in Plant Science, v. 10, p. 497.

 

NORIEGA-VASQUEZ, D.D.; Arias, P.L.; Barbosa, H.R.; Arraes, F.B.M.; Ossa, G.A.; Villegas, B.; Coelho, R.R.; Albuquerque, E.V.S.; Togawa, R.C.; Grynberg, P.; Wang, H.; Vélez, A.M.; Arboleda, J.W.; Grossi-de-Sa, M.F.; Silva, M.C.M.; Valencia-Jiménez, A. (2019). Transcriptome and gene expression analysis of three developmental stages of the coffee berry borer, Hypothenemus hampei. Scientific Reports, v. 9(1), p. 12804.

 

PAIXAO, J.F.R.; Gillet, F.X.; Ribeiro, T.P.; Bournaud, C.; Lourenço-Tessutti, I.T.; Noriega-Vasquez, D.D.; Paes-Melo, B.; Almeida-Engler, J.; Grossi-de-Sa, M.F. (2019). Improved drought stress tolerance in Arabidopsis by CRISPR/dCas9 fusion with a Histone AcetylTransferase. Scientific Reports, v. 9(1), p. 8080.

 

PRADO, G.S.; Bamogo, P.K.A.; Abreu, J.A.C.; Gillet, F.X.; Santos, V.O.; Silva, M.C.M.; Brizard, J.P.; Bemquerer, M.P.; Bangratz, M.; Brugidou, C.; Sérémé, D.; Grossi-de-Sa, M.F.; Lacombe, S. (2019). Nicotiana benthamiana is a suitable transient system for high-level expression of an active inhibitor of cotton boll weevil α-amylase. BMC Biotechnology, v. 19(1), p. 15.

2018

BOURNAUD, C.; Gillet, F.X.; Murad, A.M.; Bresso, E.; Albuquerque, E.V.S.; Grossi-de-Sa, M.F. (2018). Meloidogyne incognita PASSE-MURAILLE (MiPM) gene encodes a cell-penetrating protein that interacts with the CSN5 subunit of the COP9 signalosome. Frontiers in Plant Science, v. 9, p. 904.

HABIBI, P.; Soccol, C.R.; Okeefe, B.R.; Krumpe, L.R.H.; Wilson, J.; Macedo, L.L.P.; Faheem, M.; Santos, V.O.; Prado, G.Z.; Botelho, M.A.; Lacombe, S.; Grossi-de-Sa, M.F. (2018). Gene-silencing suppressors for high-level production of the HIV-1 entry inhibitor griffithsin in Nicotiana benthamiana. Process Biochemistry, v. 70, p. 45-54.

NARDELI, S.M.; Artico, S.; Aoyagi, G.M.; Moura, S.M.; Franca-Silva, T.; Grossi-de-Sa, M.F.; Romanel, E.; Alves-Ferreira, M. (2018). Genome-wide analysis of the MADS-box gene family in polyploid cotton (Gossypium hirsutum) and in its diploid parental species (Gossypium arboreum and Gossypium raimondii). Plant Physiology and Biochemistry, v. 127, p. 169-184.

SILVA, M.S.; Arraes, F.B.M.; Campos, M.A.; Grossi-de-Sa, M.; Fernandez, D.; Cândido, E.S.; Cardoso, M.H.; Franco, O.L.; Grossi-de-Sa, M.F. (2018). Review: potential biotechnological assets related to plant immunity modulation applicable in engineering disease-resistant crops. Plant Science, v. 270, p. 72-84.

2017

ALBUQUERQUE, E.V.S.; Petitot, A.S.; Silva, J.P.; Grossi-de-Sa, M.F.; Fernandez, D. (2017). Early responses of coffee immunity-related genes to root-knot nematode infection. Physiological and Molecular Plant Pathology, v. 100, p. 142-150.

 

ALMEIDA-GARCIA, R.; Macedo, L.L.P.; Cabral, D.N.; Gillet, F.X.; Pinto, C.E.M.; Faheem, M.; Basso, A.M.M.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2017). Nucleases as a barrier to gene silencing in the cotton boll weevil, Anthonomus grandis. PLoS One, v. 12(12), p. e0189600.

 

ANTONINO, J.D.; Pierre, O.; Coelho, R.R.; Grossi-de-Sa, M.F.; Engler, G.; Almeida-Engler, J. (2017). Application of nuclear volume measurements to comprehend the cell cycle in root-knot nematode-induced giant cells. Frontiers in Plant Science, v. 8, p. 961.

 

GILLET, F.X.; Almeida-Garcia, R.; Macedo, L.L.P.; Albuquerque, E.V.S.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2017). Investigating engineered ribonucleoprotein particles to improve oral RNAi delivery in crop insect pests. Frontiers in Physiology, v. 8, p. 1-14.

 

GILLET, F.X.; Bournaud, C.; Antonino, J.D.; Grossi-de-Sa, M.F. (2017). Plant-parasitic nematodes: towards understanding molecular players in stress responses. Annals of Botany, v. 119, p. 260-775.

 

HABIBI, P; Prado, G.S.; Pelegrini, P.B.; Hefferson, K.L.; Soccol, C.R.; Grossi-de-Sa, M.F. (2017). Optimization of inside and outside factors to improve recombinant protein yield in plant. Plant Cell Tissue and Organ Culture, v. 130, p. 449-467.

 

LISE-DE-SA, M.E.; Arraes, F.B.M.; Brito, G.; Beneventi, M.A.; Lourenço-Tessutti, I.T.; Basso, A.M.M.; Amorim, R.M.S.; Silva, M.C.M.; Faheem, M., Oliveira, N.G.; Mizoi, J.; Yamaguchi-Shinozaki, K.; Grossi-de-Sa, M.F. (2017). AtDREB2A-CA influences root architecture and increases drought tolerance in transgenic cotton. Agricultural Sciences, v. 8(10), p. 1195-1225.

 

MOURA, S.M.; Artico, S.; Lima, C.; Nardeli, S.M.; Berbel, A.; Oliveira-Neto, O.B.; Grossi-de-Sa, M.F.; Ferrándiz, C.; Madueño, F.; Alves-Ferreira, M. (2017). Functional characterization of AGAMOUS-subfamily members from cotton during reproductive development and in response to plant hormones. Plant Reproduction, v. 30(1), p. 19-39.

 

RAMOS, C.R.; Vieira, P.; Antonino, J.D.; Martin-Jimenez, C.; De-Veylder, L.; Cazareth, J.; Engler, G.; Grossi-de-Sa, M.F.; Almeida-Engler, J. (2017). Exploiting cell cycle inhibitor genes of the KRP family to control root-knot nematode induced feeding sites in plants. Plant, Cell and Environment, v. 40, p. 1174-1188.

 

RIBEIRO, T.P.; Arraes, F.B.M.; Lourenço-Tessutti, I.T.; Silva, M.S.; Lisei-de-Sa, M.E.; Lucena, W.A.; Macedo, L.L.P.; Lima, J.N.; Amorim, R.M.S.; Artico, S.; Alves-Ferreira, M.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2017). Transgenic cotton expressing Cry10Aa toxin confers high resistance to the cotton boll weevil. Plant Biotechnology Journal, v. 15(8), p. 997-1009.

2016

COELHO, R.R.; Antonino, J.D.; Firmino, A.A.P.; Macedo, L.L.P.; Fonseca, F.C.A.; Terra, W.R.; Engler, G.; Almeida-Engler, J.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2016). Vitellogenin knockdown strongly affects cotton boll weevil egg viability but not the number of eggs laid by females. Meta Gene, v. 9, p. 173-80.

 

GUIMARAES-DIAS, F.; Neves-Borges, A.C.; Conforte, A.J.; Giovanella-Kampmann, L.; Ferreira, A.V.J.; Amorim, R.M.S.; Beneventi, M.A.; Lisei-de-Sa, M.E.; Mesquita, R.O.; Rodrigues, F.A.; Nepomuceno, A.L.; Romano, E.; Loureiro, M.E.; Grossi-de-Sa, M.F.; Alves-Ferreira, M. (2016). Differential impact of acclimation and acute water deprivation in the expression of key transcription factors in soybean roots. Plant Molecular Biology Reporter, v. 34, p. 1167-1180.

 

LACERDA, A.F.; Pelegrini, P.B.; Oliveira, D.M.; Vasconcelos, E.A.; Grossi-de-Sa, M.F. (2016). Anti-parasitic peptides from arthropods and their application in drug therapy. Frontiers in Microbiology, v. 7, p. 91.

 

OLIVEIRA, R.S.; Oliveira-Neto, O.B.; Moura, H.F.; Macedo, L.L.P.; Arraes, F.B.M.; Lucena, W.A.; Lourenço-Tessutti, I.T.; Barbosa, A.A.D.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2016). Transgenic cotton plants expressing Cry1Ia12 toxin confer resistance to fall armyworm (Spodoptera frugiperda) and cotton boll weevil (Anthonomus grandis). Frontiers in Plant Science, v. 7, p. 165.

 

VILLETH, G.R.; Carmo, L.S.; Silva, L.P.; Santos, M.F.; Oliveira-Neto, O.B.; Grossi-de-Sa, M.F.; Ribeiro, I.S.; Dessaune, S.N.; Fragoso, R.R.; Franco, O.L.; Mehta, A. (2016). Identification of proteins in susceptible and resistant Brassica oleracea responsive to Xanthomonas campestris pv. campestris infection. Journal Proteomics, v. 143, p. 278-285.

2015

ALBUQUERQUE, E.V.S.; Bezerra, C.A.; Romero, J.V.; Valencia, J.W.A.; Valencia-Jiménez, A.; Pimenta, L.M.; Barbosa, A.E.A.D.; Silva, M.C.M.; Meneguim, A.M.; Lisei-de-Sa, M.E.; Engler, G.; Almeida-Engler, J.; Fernandez, D.; Grossi-de-Sa, M.F. (2015).  Seed-specific stable expression of the α-AI1 inhibitor in coffee grains and the in vivo implications for the development of the coffee berry borer. Tropical Plant Biology, v. 8, p. 98-107.

 

ARRAES, F.B.M.; Lisei-de-Sa, M.E.; Paixao, J.F.R.; Albuquerque, E.V.S.; Marin, S.R.R.; Purgatto, E.; Nepomuceno, A.R.; Grossi-de-Sa, M.F. (2015). Implications of ethylene biosynthesis and signaling in soybean drought stress tolerance. BMC Plant Biology, v. 15, p. 213-233.

 

FONSECA, F.C.A.; Firmino, A.A.P.; Macedo, L.L.P.; Coelho, R.R.; Antonino, J.D.; Oliveira-Neto, O.B.; Togawa, R.C.; Pappas, G.J.; Gois, L.A.B.; Silva, M.C.M.; Grossi-de-Sa, M.F. (2015). Sugarcane giant borer transcriptome analysis and identification of genes related to digestion. PLoS One, v. 10(4), p. e0123836.

 

LAMBRET- FROTTE, J.; Artico, S.; Muniz-Nardeli, S.; Fonseca, F.C.A.; Oliveira- Neto, O.B.; Grossi-de-Sa, M.F.; Alves-Ferreira, M. (2015). Promoter isolation and characterization of GhAO-like1, a Gossypium hirsutum gene similar to multicopper oxidases that is highly expressed in reproductive organs. Genome, v. 59(1), p. 23-36.

 

LOURENÇO-TESSUTTI, I.T.;  Antonino, J.D.; Martins-de-Sa, D.; Viana, A.A.B.;  Carneiro, R.M.D.G.; Togawa, R.C.;  Almeida-Engler, J.;  Batista, J.A.N.; Silva, M.C.M.; Fragoso, R.R.; Grossi-de-Sa, M.F. (2015). Knock-down of heat-shock protein 90 and isocitrate lyase gene expression reduced root-knot nematode reproduction. Phytopathology, v. 105(5), p. 628-637.

 

ROCHA, R.O.; Moraes, J.K.S.; Oliveira, J.T.A.; Oliveira, H.D.; Sousa, D.O.B.; Souza, C.E.A.; Moreno, F.B.; Monteiro-Moreira, A.C.O.; Antonino, J.D.; Grossi-de-Sa, M.F.; Vasconcelos, I.M. (2015). Proteome of soybean seed exudates contains plant defense-related proteins active against the root-knot nematode Meloidogyne incognita. Journal of Agricultural and Food Chemistry, v. 63(22), p. 5335-5343.

PATENTS

 

ALVES-FERREIRA, M.; Grossi-de-Sa, M.F.; Lambret, J.; Nardeli, S.M.; Artico, S. Compositions and method for modifying gene expression using a promoter of genes specific to plant flowers and fruit. WO 2014/000075 A2. Deposit: June 27, 2012. Publication: January 3, 2014.

 

ALVES-FERREIRA, M.; Waltenberg, F.P.C.; Romano, E.; Grossi-de-Sa, M.F. Utilização do gene homeobox de café cahb12 na produção de plantas transgênicas mais tolerantes ao déficit hídrico e estresse salino. WO 2012/061911 A9. Deposit: November 8, 2011. Publication: May 18, 2012.

 

CARLINI, C.R.R.S.; Ferreira, C.T.S.; Moraes, M.G.; Mulinari, F.; Silva, M.A.F.; Grossi-de-Sá, M.F.; Kurtenbach, E. Toxina praguicida, construção gênica e método de controle de pragas. PI 0403435-0 ADeposit: April 8, 2004. Publication: August 1, 2006.

 

GROSSI-DE-SA, M.F.; Coelho, R.R.; Firmino, A.A.P.; Macedo, L.L.P; Silva, M.C.M.; Lourenço-Tessutti, I.T. Método e composições para controle de insetos-praga em plantas por meio do silenciamento de genes da família da quintina sintase e da vitelogenina bem como alternativamente pela expressão do gene de uma toxina Cry. BR 102013032649-6 A2. Deposit: December 18, 2013. Publication: February 10, 2016.

 

GROSSI-DE-SA, M.F.; Firmino, A.A.P.; Silva, M.C.M.; Martins-de-Sa, D.; Coelho, R.R.; Macedo, L.L.P.; Lourenço-Tessuti, I.T. Método e composições para controle genético de insetos-praga em plantas de algodão através do silenciamento de genes de lacases. WO 2014/100878 A3. Deposit: December 27, 2013. Publication: July 3, 2014.

 

GROSSI-DE-SA, M.F.; Guimaraes, L.M.; Batista, J.A.N.; Viana, A.A.B.; Fragoso, R.R.; Rocha, T.L. Composições e métodos para modificar a expressão de genes usando o promotor do gene da proteína de conjugação à ubiquitina de plantas de algodoeiro. PI 0701230-6US 2013/0152226 A1. Deposit: February 5, 2007 (BR) and February 19, 2013 (US). Patent granted: June 26, 2018 (BR) and June 13, 2013 (US).

 

GROSSI-DE-SA, M.F.; Macedo, L.L.P.; Pinto, C.E.M.; Leite, A.G.B.; Silva, M.C.M.; Lourenço-Tessutti, I.T.; Morgante, C.V. Método para produzir planta resistente a inseto praga e moléculas de ácido nucleicos utilizado para obtenção de tal planta através de dsRNAs relacionados a ecdise. PI 102020004312-9. Deposit: March 3, 2020.

 

GROSSI-DE-SA, M.F.; Macedo, L.L.P.; Silva, M.C.M.; Almeida-Garcia, R.; Silva, L.P.; Vila, A. Pesticide. WO 2020/007450 A1. Deposit: July 7, 2018, Publication: January 9, 2020.

 

GROSSI-DE-SA, M.F.; Oliveira, G.R.; Silva, M.C.M.; Rocha, T.L.; Magalhaes, M.T.Q. Molécula de ácido nucléico isolada, construção gênica, vetor, célula transgênica, método para obtenção de uma célula e de uma planta transgênica. PI 0906128-2 B1. Deposit: July 24, 2009. Patent granted: March 17, 2020.

 

GROSSI-DE-SA, M.F.; Romano, E.; Fragoso, R.R.; Silva, M.C.M.; Ferreira, A.V.J.; (2013). Cassete de expressão para indução de resistência a múltiplas espécies de nematóides em plantas, métodos e plantas que o utilizam. WO 2014/197951 A2. Deposit: June 11, 2013. Publication: December 18, 2014.

 

GROSSI-DE-SA, M.F.; Silva, M.C.M.; Del-Sarto, R.P.; Rocha, T.L. Mutantes de inibidores de alfa amilases isolados de Phaseolus vulgaris com propriedades de controlar insetos-praga, composições contendo tais mutantes e métodos de obtenção dos mesmos e de linhagens transgênicas. PI 1102841-6Deposit: June 8, 2011. Patent granted: November 26, 2018.

 

GROSSI-DE-SA, M.F.; Silva, M.C.M.; Macedo, L.L.P.; Firmino, A.A.P.; Coelho, R.R.; Lourenço-Tessuti, I.T. Método e composições para controle genético de insetos-praga em plantas de algodão através do silenciamento de genes de quitina sintases. BR 102012033539-5 A2US 10182571 B2 and WO 2014/100879 A2. Deposit: December 28, 2012 (BR), December 27, 2013 (US) and June 27, 2013 (WO).  Publication: August 18, 2015 (BR), January 22, 2019 (US) and January 3, 2014 (WO).

 

GROSSI-DE-SA, M.F.; Silva, M.C.M.; Fonseca, F.C.A.; Macedo, L.L.P.; Lourenco, I.T.; Albuquerque, E.V.S. Aparato e método de criação de larvas de insetos em laboratório. BR 1020130331120 B1. Deposit: December 20, 2013. Patent granted: November 24, 2020.

 

GROSSI-DE-SA, M.F.; Silva, M.C.M.; Gomes-Jr, J.E.; Lourenço-Tessuti, I.T.; Macedo, L.P.P.; Lucena, W.A.; Fonseca, F.C.A. Moléculas variantes sintéticas de toxinas Cry1Ia12 com propriedades de controlar insetos-praga, composições contendo tais mutantes e método de utilização dos mesmos. WO 2014-100880 A3. Deposit: 02/12/2012. Publication: July 3, 2014.

 

HEMERLY, A.S.; Cavalcanti, P.F.; Gong, P.; Nelissen, H.; Inze, D.; Grossi-de-Sa, M.F.; Basso, M.F.; Morgante, C.V.; Lisei-de-Sa, M.E. Method for promoting an increase in plant biomass, productivity, and drought resistance. US 2020/0347399 A1. Deposit: May 4, 2020. Publication: November 5, 2020.

 

MACEDO, L.L.P.; Grossi-de-Sa, M.F.; Silva, M.C.M.; Almeida-Garcia, R.; Mendes, R.A.G.; Albuquerque, E.V.S. Increasing the efficiency of supression of gene expression by means of the use of RNA molecules with a stabilized structure. BR 10201700690-4 A2WO 2018/184083 A1. Deposit: April 4, 2017 (BR) and March 29, 2018 (US). Publication: October 30, 2018 (BR) and November 11, 2018 (US).

 

MESSENBERG, P.G.; Grossi-de-Sa, M.F. Métodos para detecção e identificação de Curtobacterium flaccumfaciens pv flaccumfaciens em uma amostra biológica e método de certificação de sementes. PI 9806477-0. Deposit: June 23, 1998. Patent granted:  April 29, 2014.

 

OLIVEIRA, G.R.; Marra, B.M.; Grossi-de-Sa, M.F. Processo de uso industrial e agronômico de ácidos graxos e/ou borra de algodão e/ou borra de soja e/ou borra de mamona e demais borras e seus componentes, como molécula(s), com efeito, nematicida e/ou nematostático e/ou de controle de nematóides. BR 102012007851 A2Deposit: April 5, 2012. Publication: November 24, 2012.

 

ROCHA, T.L.; Evaristo, R.G.S.; Grossi-de-Sa, M.F.; Silva, M.C.M.; Polez, V.L.P.; Roessner, U.; Bacic, T. Nematotoxic composition of synergistic effect, use of a nematotoxic composition of synergistic effect. US 9750247 B2CN 105007725 BDeposit: December 26, 2013 (US and CH). Patent granted: September 5, 2017 (US) and April 4, 2019 (CH).

 

SCHERRER, K.; Grossi-de-Sa, M.F. Monoclonal antibodies against prosomal proteins (covering any p-Mab against prosomes). EP 0434670 B1. Deposit: August 29, 1986. Publication: June 11, 1997.

 

SCHERRER, K.; Grossi-de-Sa, M.F. Monoclonal antibodies against prosomal proteins (covering p27k and p31k p-Mabs). EP 0219368 B1Deposit: August 29, 1986. Publication: March 11, 1992.

 

SOUZA, D.S.L.; Silva, M.C.M.; Grossi-de-Sa, M.F.; Evaristo, R.G.S.; Rocha, T.L.; Bacic, T.; Roessner, U.; Polez, V.L.P. Composição nematotóxica de efeito sinérgico, uso de composição nematotóxica de efeito sinérgico. BR 10201203314-6 A2. Deposit: December 26, 2012. Patent granted: August 26, 2014.

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